Redesigning culturally tailored intervention in the precision health era: Self-management science context


      • The major limitations of current cultural tailoring methodology stem from increased complexity in cultural identity, underdeveloped conceptual work and a lack of rigor in the operationalization of tailoring strategies.
      • Core principles of precision health such as the personalization of interventions can be applied to overcome the weaknesses in current cultural tailoring methodology and practice.
      • We recommend precision health methodology to as a tool for advancing the science of cultural tailoring and health equity research.



      Nurse scientists have significantly contributed to health equity and ensuring cultural tailoring of interventions to meet unique needs of individuals. Methodologies for cultural tailoring of self-mangament interventions among marginalized populations have limitedly accommodated intersectionality and group heterogeneity when addressing health needs.


      Identify methodological limitations in cultural tailoring of interventions among priority populations and issue recommendations on cultural elements that researchers can target to ensure valid cultural tailoring approaches.


      Synthesis of literature on health equity, self-management, and implementation and dissemination research.


      Among priority populations, intersectionality and group heterogeneity has made group-based cultural tailoring approaches less effective in eliciting desirable health outcomes. Precision health methodology could be useful for cultural tailoring of interventions due to the methodology's focus on individual-level tailoring approaches.


      We offer ways to advance health equity research using precision health approaches in cultural tailoring through targeting unique elements of culture and relevant psychosocial phenotypes.


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